Prof. Xian Yanfang Lisa

Xian Yanfang Lisa
 

Prof. Lisa Xian

position Position Research Assistant Professor
place Office Room 101-J, Li Wai Chun Building, Chung Chi College, The Chinese University of Hong Kong, Hong Kong
tele num Tel. (852) 3943 5357
fax Fax. (852) 3942 0941
email Email This email address is being protected from spambots. You need JavaScript enabled to view it.

Resume (Education and Working Experience)

Education:

  1. 2004 B.S. (Chinese Medicine),Guangzhou University of Traditional Chinese Medicine
  2. 2007 M.Phil. (Chinese Medicine),Guangzhou University of Traditional Chinese Medicine
  3. 2013 PhD (Chinese Medicine),The Chinese University of Hong Kong

Working Experience:

  1. 2007 - 2010 Research Assistant, School of Chinese Medicine, CUHK
  2. 2013 - 2017 Postdoctoral Fellow, School of Chinese Medicine, CUHK
  3. 2017 - present Research Assistant Professor, School of Chinese Medicine, CUHK
  

Research Interest


The pharmacological activities of Chinese herbal medicine in Alzheimer's disease, Parkinson's disease, depression and cancers related to the urinary system and digestive system.

 

Selected Publications

  1. Qu C, Li QP, Su ZR, Ip SP, Yuan QJ, Xie YL, Xu QQ, Yang W, Huang YF, Xian YF*, Lin ZX. Nano-Honokiol Ameliorates the Cognitive Deficits in TgCRND8 Mice of Alzheimer's Disease via Inhibiting Neuropathology and Modulating Gut Microbiota. J Adv Res. 2021 Mar 31. DOI:10.1016/j.jare.2021.03.012. Online ahead of print.
  2. Zhang ZB, Ip SP, Cho WCS, Ng ACF, Hu Z, Huang YF, Luo DD, Xian YF*, Lin ZX. Herb-drug interactions between androgenic Chinese herbal medicines and androgen receptor antagonist on tumor growth: Studies on two xenograft prostate cancer animal models. Phytother Res. 2021 Jan 13. DOI:10.1002/ptr.7020. Online ahead of print.
  3. Chen Y, Xian YF*, Loo S, Chan WY, Liu L, Lin ZX. Anti-atopic dermatitis effects of dictamni cortex: Studies on in vitro and in vivo experimental models. Phytomedicine 2021;82:153453. DOI:10.1016/j.phymed.2020.153453.
  4. Yang W, Liu Y, Xu QQ, Xian YF*, Lin ZX. Sulforaphene Ameliorates Neuroinflammation and Hyperphosphorylated Tau Protein via Regulating the PI3K/Akt/GSK-3β Pathway in Experimental Models of Alzheimer's Disease. Oxid Med Cell Longev 2020;2020:4754195. DOI:10.1155/2020/4754195.
  5. Xian YF*, Qu C, Liu Y, Ip SP, Yuan QJ, Yang W, Lin ZX. Magnolol Ameliorates Behavioral Impairments and Neuropathology in a Transgenic Mouse Model of Alzheimer's Disease. Oxid Med Cell Longev 2020;2020:5920476. DOI:10.1155/2020/5920476
  6. Xian Y, Zhang J, Bian Z, Zhou H, Zhang Z, Lin Z, Xu H. Bioactive natural compounds against human coronaviruses: a review and perspective. Acta Pharm Sin B 2020;10(7):1163-74. DOI:10.1016/j.apsb.2020.06.002.
  7. Li HQ, Ip SP, Yuan QJ, Zheng GQ, Tsim KKW, Dong TTX, Lin G, Han Y, Liu Y, Xian YF*, Lin ZX. Isorhynchophylline ameliorates cognitive impairment via modulating amyloid pathology, tau hyperphosphorylation and neuroinflammation: Studies in a transgenic mouse model of Alzheimer's disease. Brain Behav Immun 2019;82:264-78. DOI:10.1016/j.bbi.2019.08.194.
  8. Xian YF*, Ip SP, Li HQ, Qu C, Su ZR, Chen JN, Lin ZX. Isorhynchophylline exerts antidepressant-like effects in mice via modulating neuroinflammation and neurotrophins: involvement of the PI3K/Akt/GSK-3β signaling pathway. FASEB J 2019;33(9):10393-408. DOI:10.1096/fj.201802743RR.
  9. Xian YF, Hu Z, Ip SP, Chen JN, Su ZR, Lai XP, Lin ZX. Comparison of the anti-inflammatory effects of Sinapis alba and Brassica juncea in mouse models of inflammation. Phytomedicine 2018;50:196-204. DOI:10.1016/j.phymed.2018.05.010.
  10. Lai ZQ, Ip SP, Liao HJ, Lu Z, Xie JH, Su ZR, Chen YL, Xian YF, Leung PS, Lin ZX. Brucein D, a Naturally Occurring Tetracyclic Triterpene Quassinoid, Induces Apoptosis in Pancreatic Cancer through ROS-Associated PI3K/Akt Signaling Pathway. Front Pharmacol 2017;8:936. DOI:10.3389/fphar.2017.00936.

* Corresponding Author
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